Inhibition of monoamine oxidase by substituted hydrazines

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Inhibition of monoamine oxidase by stilbenes from Rheum palmatum

Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-O-β-D-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). Anti-monoamine oxidase (MAO) activities of compounds 1–8 were tested. Compounds 1 and 8 showed sig...

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Inhibition of monoamine oxidase by stilbenes from Rheum palmatum

Seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of Rheum palmatem. Their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-O-β-D-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). Anti-monoamine oxidase (MAO) activities of compounds 1–8 were tested. Compounds 1 and 8 showed sig...

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inhibition of monoamine oxidase by stilbenes from rheum palmatum

seven stilbenes and one catechin were bioactivity-guidedly isolated from the rhizomes of rheum palmatem. their structures were identified as piceatannol(1), resveratrol(2), piceid(3), rhapontigenin(4), piceatannol-3'-o-β-d-glucopyranoside(5), rhaponticin(6), catechin(7) and desoxyrhapontigenin(8). anti-monoamine oxidase (mao) activities of compounds 1–8 were tested. compounds 1 and 8 showe...

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Monoamine oxidase inhibition.

Introduction The discovery that inhibitors of monoamine oxidase (EC 1.4.3.4.; MAO) are antidepressants (see [ l ] for a review) has resulted in the synthesis of large numbers of inhibitors, several of which have proved to be valuable in clinical use. Such work was given added impetus when it was recognized that there are two monoamine oxidases in most mammalian tissues, MAO-A and MAO-B, with di...

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Inhibition of monoamine oxidase B by selec - tive 7 - substituted coumarin derivatives

Introduct ion Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the most frequent neurodegenerative disorders and cause of disability among western societies.1 Interest in the selective inhibition of monoamine oxidase B (MAO-B) has increased in the last years due to their therapeutic potential in this age related neurodegeneration. Currently, acetyl cholinesterase (AChE) inhibitors are ...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1972

ISSN: 0306-3283

DOI: 10.1042/bj1280913